The Ultimate Sustanon Guide

What Is Sustanon?

Sustanon –also known as Sustanon 250- is a testosterone-based anabolic compound; developed and trademarked by Organon Pharmaceuticals.

The oil-based injectable was originally intended to work as a fast-acting TRT compound that could generate long-lasting effects while reducing injection frequency.


Although it was originally developed specifically for Testosterone Replacement Therapy (TRT); its benefits and popularity would make it a favorite among bodybuilders.

The steroid is composed out of four different testosterone esters: two that are short-acting, one that is medium-acting, and a final one that’s long-acting.

Sustanon Formula

Testosterone Propionate – 30mg

Testosterone Phenylpropionate – 60mg

Testosterone Isocaproate – 60mg

Testosterone Decanoate – 100mg

If we add up the numbers above, it’s easy to understand where Sustanon 250 gets its name from. This is even easier to comprehend when we compare it to Sustanon 100.

Sustanon 100 was a “toned down” version of Sustanon 250 that was discontinued way back in 2009.

The main difference between Sustanon 250 and Sustanon 100 was the lack of testosterone decanoate in the latter.

Sustanon 250

We’ve just mentioned that Sustanon 250 receives its name from its formula, that combines 250mg of different testosterone esters.

The intended purpose of creating such a compound was nothing more than to develop an injectable steroid that could generate fast results – and maintain them for a reasonable amount of time.

It was originally believed that combining esters with different active lives (short, medium, and long) would lead to the creation of a potent -but stable- compound.

Although at first, the attempt appeared to be successful; it was later discovered that the formula didn't behave as originally expected.

Sustanon 250 Presentation

As soon as the steroid made it into the bloodstream, test levels would peak; only to slowly taper down right after.

This meant that the human body would have to be injected in a similar fashion (frequency) as other short-acting esters in order to maintain hormone stability.

For this reason, some people believe that Sustanon doesn't offer any significant benefits; compared to other simpler testosterone compounds.

Let’s take a good look at each of the individual testosterone esters that make up the formula, as it will help us better understand its nature.

Testosterone Propionate

Tetosterone Propionate is widely considered to be the mildest of the different existing testosterone esters. The hormone is quick-acting and can generate results in as little as 2-3 days.

testosterone propionateAthletes commonly used it for both bulking and cutting cycles because it’s a potent muscle builder that doesn’t tend to cause water retention.

One of its biggest downsides is the fact that it needs to be injected every day -or every other day- for maximum results.

Female bodybuilders tend to use this form of testosterone (on its own) over the rest, due to its short active life that allows for quick dosage modification and possible side-effect reduction.

Testosterone Phenylpropionate

Testosterone Phenylpropionate and Testosterone Propionate represent the small esters in the Sustanon formula.

testosterone phenylpropionateThis means that phenylpropionate –just like propionate- will technically generate quick results.

The main difference -according to a few online sources- suggests that phenylpropionate can be administered twice a week; versus propionate that's injected daily or every other day.

Some bodybuilders prefer this form of test -over propionate- because they believe that it’s stronger and less painful to administer.

Testosterone Isocaproate

Remember how it was mentioned that both propionate and phenylpropionate were small esters that were scientifically developed to generate quick results? Testosterone Isocaproate is a bit different.

testosterone isocaproate When Sustanon was first envisioned, the minds behind it wanted to develop a compound that could generate fast results that would also last a prolonged period of time, right?

In order to achieve this, they thought that they needed to combine short, medium, and long-acting esters. In this equation, isocaproate would fill the middle role.

Testosterone isocaproate offers similar benefits to those of the other two compounds but differentiates itself by having a longer active life.

Testosterone Decanoate

Testosterone Decanoate is the last hormone in the formula and one of the largest single-ester compounds known to man.

testosterone decanoateIndividually and commercially sold for veterinary purposes as Neotest 250; testosterone decanoate is the slowest-releasing form of testosterone in the entire formula.

Although the compound -just like the rest- is both highly anabolic and androgenic; testosterone decanoate was never intended to treat low testosterone on its own.

For this exact reason, it’s extremely difficult to find an isolated form of the hormone -black market included- because it’s mostly found in different Sustanon compounds.

Sustanon Dosages

Dosages for the oil-based injectable will greatly vary, depending on its intended purposes and the person who uses it.

According to various online forums, it’s not uncommon to see men using 250mg every 10-30 days for TRT.

syringe and vials

Illegally, some bodybuilders have been known to use anywhere between 200-250mgs per week. Some have taken it to the extreme and use upwards of a gram a week.

Although the active life of the compound is approximately 21 days; the fact that its effects begin to taper down after injection is (arguably) the main reason why athletes inject it with higher frequency.

Sustanon Benefits

Before we continue with the benefits, let’s backtrack a little.

On paper, the steroid was originally created as a new and improved form of TRT that could treat men with low testosterone, more efficiently.

It was also believed that combining four different types of testosterone into one formula would generate greater benefits while reducing injection frequency.

susts 250 benefits

Although its hard to dispute its effectiveness; it's safe to say that it fell short and didn’t work as originally expected.

On the other hand -and like all steroids- it would quickly make its way into the hands of bodybuilders as a performance enhancement drug.

It goes without saying that its popularity outside the medical field –although illegal- has proven to be exponential.

Testosterone Replacement Therapy with Sustanon 250

Sustanon 250 was originally created -and used- specifically for TRT due to its lightning fast results and long-lasting testosterone release that could be achieved with infrequent injections.

It was later discovered that although test levels peaked quite early (after injection); these were hard to maintain, as overall levels steadily decreased soon after.

Testosterone Replacement Therapy with Sustanon

This meant that in order to maintain a balanced amount of testosterone in the bloodstream; the compound would have to be injected almost as frequently as any other form of TRT.

This would lead some people to believe that it would be much easier to use a simple compound -such as Testosterone Cypionate- that only needs to be injected once every 2-3 weeks.

Sustanon Use in Bodybuilding

Even though Sustanon didn't quite work as originally expected; its existence in the medical field has been widely successful, nonetheless.

With that being said, bodybuilding is where its biggest fan base can be found.

Sust 250 has been used by bodybuilders and strength athletes -of all levels- for performance enhancement with much (controversial) success.

Performance Enhancement with Sustanon

Regardless of its illegal status, men and women have used the hormone in order to build their physiques and drastically enhance their performance.

Any form of testosterone -Sustanon included- will have a direct impact on the body’s ability to build muscle, develop strength, and enhance protein synthesis.

The steroid can also increase nitrogen retention and red blood cell production, enhance sex drive – and greatly improve physical endurance.

Sustanon Side Effects

As you would expect from any anabolic steroid, this one isn't any different – as it's known to generate its fair share of health issues, under the incorrect guidance.

This shouldn’t come as a surprise as it’s a well-known fact that any type of exogenous hormone can have a direct negative impact on the human body.

If you take into consideration that Sustanon combines four types of exogenous testosterone; you could say that it's a potential recipe for disaster.

steroids side effects

Generally speaking, Sustanon could best be described as a scientific testosterone cocktail that’s just as powerful as it is dangerous.

Not as serious, but still concerning, is the fact that Sustanon injections are quite painful and known to cause irritation and swelling.

Some bodybuilders will completely eliminate it from their cycles due to the amount of pain and discomfort that it can cause them.

Side Effects in Men

Testosterone has an extreme tendency to convert into estrogen, thanks to the aromatize enzyme. This means that you will be likely to suffer from water retention and gynecomastia during its use.

Although you could use an aromatase inhibitor or a selective estrogen receptor modulator to reverse these issues – you’ll still have to deal with a series of androgenic side effects.

side effects men

Common androgenic side effects include body hair growth, baldness, and acne; due to testosterone being converted into dihydrotestosterone.

The body’s natural test production can also be completely suppressed; which could lead to testicular atrophy.

Side Effects in Women

It’s common knowledge that female bodybuilders have been using anabolic steroids to build their physiques for a very long time.

Sustanon contains short, medium, and long-acting esters – which poses an automatic risk for the female sex.

An ester that’s slow-acting can stay inside the human body for up to three weeks; which makes it difficult for anyone to adjust the dosage in order to stop/reverse the appearance of side effects.

female side effects

That’s why women typically like to stick to shorter-acting esters that are in and out of the body in only a few days.

Common side effects in women include body/facial hair growth, deepening of the voice, and an enlarged clitoris.

It’s worth mentioning that the same effects can also happen by using a slow-acting ester – but the probability is a lot higher by using Sust 250.


Sustanon is an anabolic compound that’s made by scientifically combining four types of testosterone; propionate, phenylpropionate, isocaproate, and decanoate.

It was originally developed as a stronger -and more efficient type- of TRT that could limit the frequency of injections.

This, thanks to its ability to stay in the bloodstream for a prolonged period of time.

It was later discovered that its chemical composition wouldn't actually play a significant role in maintaining a (prolonged) balanced level of testosterone in the bloodstream.

bodybuilder flexing bicep

This didn’t mean that it wasn’t effective as a TRT treatment option; it just meant that it wasn’t as effective as it was originally believed.

Although the oil-based compound can only be legally used within the medical field – it doesn’t stop bodybuilders from acquiring it in the black market.

Bodybuilders and strength athletes –male and female- have taken advantage of its anabolic properties for a very long time in order to build their physiques and enhance their overall performance.

Abusing the complex hormone compound can potentially generate a series of unwanted side effects that are not easily reversible.


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